← Compounds
AOD-9604
peptide · headlineResearch use onlyStimulates lipolysis
Summary
AOD-9604 is a modified peptide fragment of human growth hormone designed to stimulate fat metabolism while avoiding the adverse effects associated with hGH therapy. It promotes lipolysis, inhibits fat formation, and has a proven safety profile in human studies. It has been explored in clinical research for obesity and metabolic modulation.
How it works
- Stimulates lipolysis
- Inhibits lipogenesis
- Mimics metabolic region of hGH without affecting IGF-1 levels
Dosing
- unit: mcglow dose: 400frequency: Once dailyhigh dose: 600standard dose: 500administration route: Subcutaneous (SQ)
- unit: mglow dose: 0.5frequency: Once dailyhigh dose: 1.5standard dose: 1administration route: Oral
Cycling
- Inject 500 mcg in the morning while fasted. Cycle 20 days on, 10 days off, or up to 12 weeks with 2-week break. Effects build gradually; consistent use required for best outcomes.
Side effects
long term: ["Development terminated in 2007 — larger Phase IIb trial (536 subjects, 24 weeks) failed to achieve statistical significance; drug not FDA-approved"]
Chemistry & PK
sequence: Tyr-hGH177-191
half life: Approximately 4 hours
degradation: Metabolized by proteolytic enzymes in peripheral tissue
molecular weight: 1813.1
molecular formula: C112H179N29O35S
tissue specificity: Primarily targets adipose tissue; also shows chondrocyte activation in cartilage
Verified citations
2 · PubMed-checked- AOD-9604 Metabolic.reviewPMID 15134286 ↗
- Obesity drugs in clinical development.reviewPMID 16625817 ↗
Used for
No condition evidence rows yet.
Legal / compounding
Research use only
Legal status is a hard gate: non-compoundable or delisted agents cannot be filled and are blocked from protocol export. Keep 503A status current.