← Compounds
Pinealon
peptide · headlineResearch use onlyCrosses the blood-brain barrier and enhances neural gene expression
Summary
Pinealon is a synthetic tripeptide bioregulator derived from pineal and brain tissue that promotes neuroprotection, memory consolidation, and pineal gland function. It is used in aging, cognitive decline, and circadian rhythm regulation protocols and has demonstrated antioxidant and geroprotective properties in preclinical studies.
How it works
- Crosses the blood-brain barrier and enhances neural gene expression
- Supports pineal gland-mediated hormonal balance (e.g., melatonin)
- Increases resistance of neurons to oxidative stress and metabolic damage
- Stabilizes bioelectrical activity in cerebral cortex and hippocampus
Dosing
- unit: mcglow dose: 3frequency: Dailyhigh dose: 10standard dose: 5administration route: Subcutaneous (SQ)
Cycling
- Administer daily for 10–20 days. Repeat every 4–6 months for cognitive maintenance or aging support.
Side effects
common: ["Headaches (tension-like)","Vivid dreams/insomnia if taken late","Mild anxiety, dizziness, nausea","Changes in bowel habits"]
Chemistry & PK
sequence: Lys-Gly-Asn
half life: Approximately 20 minutes
degradation: Metabolized by tissue peptidases and liver enzymes
molecular weight: 200.25
molecular formula: C10H16N2O3
tissue specificity: Targets pineal gland, hippocampus, and neocortex
Verified citations
2 · PubMed-checked- Effect of synthetic peptides on aging of patients with organic brain syndrome.clinicalPMID 26390612 ↗
- EDR Peptide: Mechanism of Gene Expression Regulation in Alzheimer's Disease.mechanismPMID 33396470 ↗
Used for
No condition evidence rows yet.
Legal / compounding
Research use only
Legal status is a hard gate: non-compoundable or delisted agents cannot be filled and are blocked from protocol export. Keep 503A status current.