Snap-8

Snap-8 is a topical cosmetic peptide used to reduce the appearance of fine lines and wrinkles by inhibiting facial muscle contractions. It mimics the effect of Botox but is applied non-invasively, making it ideal for long-term wrinkle control and skin smoothing.

• Inhibits SNARE complex assembly, reducing neurotransmitter release
• Limits muscle contraction in the facial region, reducing expression lines
• Blocks calcium-dependent vesicle fusion at the neuromuscular junction
• Mimics botulinum-like muscle relaxation effects without injection

• unit: mcg

  low dose: 200

  frequency: Twice daily

  high dose: 500

  standard dose: 300

  administration route: Topical

• Apply twice daily to wrinkle-prone areas. Continuous use recommended for best cosmetic effect; maintenance cycles may continue indefinitely.

common: ["Mild irritation at higher concentrations (>3–10%) (user-reported)","Mild reactions when combined with retinoids and vitamin C (user-reported)"]

sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2

half life: Estimated under 24 hours for topical stability

degradation: Primarily broken down by proteases at the skin surface

molecular weight: 1075.16

molecular formula: C41H70N16O16S

tissue specificity: Acts locally at dermal neuromuscular junctions in the facial area