Tadalafil

on-label Rx · comparatorFDA-approved

PDE5 inhibition → vasodilation

Summary

PDE5 inhibitor for erectile/vascular function; pairs with PT-141 (central + vascular arousal). Also used low-dose daily for vascular healthspan.

How it works

PDE5 inhibition → ↑ cGMP → vasodilation

Dosing

unit: mg
frequency: daily or PRN
high dose: 20
standard dose: 5
administration route: Oral

Cycling

Continuous or on-demand

Side effects

common: ["Headache","Flushing","Nasal congestion"]

warnings: ["Contraindicated with nitrates"]

Verified citations

2 · PubMed-checked

Direct comparison of tadalafil with sildenafil for erectile dysfunction: meta-analysis.clinicalPMID 28741090 ↗
Tadalafil in the treatment of erectile dysfunction.reviewPMID 14622501 ↗

Used for

Legal / compounding

FDA-approved

Legal status is a hard gate: non-compoundable or delisted agents cannot be filled and are blocked from protocol export. Keep 503A status current.