← Compounds
Thymalin
peptide · headline503A compoundedModulates immune cell activity by enhancing T-cell differentiation and thymic function
Summary
Thymalin is a thymic peptide complex known for its potent immunoregulatory effects, supporting T-cell maturation, reducing inflammation, and improving thymic function. It has been investigated for anti-aging, immune optimization, and cancer adjunctive support.
How it works
- Modulates immune cell activity by enhancing T-cell differentiation and thymic function
- Reduces systemic inflammation by suppressing pro-inflammatory cytokines
- Supports thymus gland function, crucial for maintaining immune homeostasis during aging
- Zinc-dependent activity: Thymulin requires sufficient zinc levels for optimal biological activity
Dosing
- unit: mglow dose: 5frequency: dailyhigh dose: 20standard dose: 10administration route: Subcutaneous (SQ)
Cycling
- Initial loading: 10 mg daily for 5–10 days. Maintenance: 1–2x weekly for 6–12 weeks. Repeat up to 3 cycles annually for immune support and thymic rejuvenation.
Side effects
common: ["Localized pain at injection site"]
warnings: ["Use under medical supervision in patients with serious immune disorders"]
long term: ["No known long-term issues with clinical use"]
Chemistry & PK
sequence: Glu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn
half life: Less than 30 minutes
degradation: Predominantly by blood proteases
molecular weight: 857
molecular formula: C33H54N12O15
tissue specificity: Targets thymus and immune-related tissues
Verified citations
3 · PubMed-checked- Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells.mechanismPMID 33237528 ↗
- Peptides of pineal gland and thymus prolong human life.clinicalPMID 14523363 ↗
- The Influence of KE and EW Dipeptides in Thymalin on Gene Expression in COVID-19.mechanismPMID 37686182 ↗
Used for
No condition evidence rows yet.
Legal / compounding
503A compounded
Legal status is a hard gate: non-compoundable or delisted agents cannot be filled and are blocked from protocol export. Keep 503A status current.