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Thymogen

peptide · headlineResearch use only

Stimulates thymus-derived lymphocyte differentiation

Summary

Thymogen is a thymic-derived short peptide immunomodulator that promotes T-cell activity, immune rebalancing, and resistance to infection. It is widely used in Eastern European protocols to support immune function, particularly in cases of immunodeficiency, chronic infection, or age-related immune decline.

How it works

  • Stimulates thymus-derived lymphocyte differentiation
  • Enhances T-cell receptor expression and immunologic memory
  • Regulates cytokine production and immune signaling cascades

Dosing

  • unit: mcg
    low dose: 50
    frequency: Once daily
    high dose: 150
    standard dose: 100
    administration route: Subcutaneous (SQ)

Cycling

  • Administer daily for 10–14 days. Repeat cycle every 3–6 months or as needed based on immune status.

Side effects

common: ["Redness or soreness at injection site","Mild fatigue"]
warnings: ["Not recommended for use in autoimmune disorders due to potential for immune overstimulation"]
long term: ["May lead to immune exhaustion or imbalance with extended use; monitor in chronic administration"]

Chemistry & PK

sequence: H-Ala-Lys-Glu-Asp-OH
half life: Approximately 60 minutes
degradation: Broken down by proteases in plasma and liver
molecular weight: 453.53
molecular formula: C22H33N6O5
tissue specificity: Preferentially targets thymus, spleen, and peripheral immune cells

Verified citations

2 · PubMed-checked
  • Thymogen in the treatment of type-1 diabetes mellitus.clinicalPMID 9026934
  • The efficacy of using thymogen in an experimental infection caused by Yersinia enterocolitica.preclinicalPMID 7660690

Used for

No condition evidence rows yet.

Legal / compounding

Research use only

Legal status is a hard gate: non-compoundable or delisted agents cannot be filled and are blocked from protocol export. Keep 503A status current.