← Compounds
Vesugen
peptide · headlineResearch use onlyRegulates gene expression of vascular wall endothelial cells
Summary
Vesugen is a synthetic peptide studied for its potential vascular-regulatory effects. It is derived from DNA-regulating peptide complexes and has been evaluated in Russia for its effects on endothelial function and cardiovascular aging.
How it works
- Regulates gene expression of vascular wall endothelial cells
- Supports extracellular matrix remodeling and vascular elasticity
- May stabilize microcirculation and reduce endothelial permeability
Dosing
- unit: mglow dose: 0.5frequency: Once daily for 10–20 dayshigh dose: 2standard dose: 1administration route: Subcutaneous (SQ)
Cycling
- Administer daily for 10–20 days. Repeat cycle every 3–6 months for vascular maintenance or recovery.
Side effects
common: ["Mild nausea (<5%), occasional headaches (<3%), minor digestive upset (user-reported)"]
warnings: ["Drug interactions with statins/ACE inhibitors untested"]
Chemistry & PK
sequence: Lys-Glu-Asp
half life: Estimated 3–4 hours
degradation: Metabolized by renal and hepatic peptidases
molecular weight: 390.39
molecular formula: C15H26N4O8
tissue specificity: Acts primarily on capillaries, vascular smooth muscle, and endothelial tissues
Verified citations
2 · PubMed-checked- Peptides tissue-specifically stimulate cell differentiation during their aging.mechanismPMID 22808515 ↗
- Effect of synthetic peptides on aging of patients with organic brain syndrome.clinicalPMID 26390612 ↗
Used for
No condition evidence rows yet.
Legal / compounding
Research use only
Legal status is a hard gate: non-compoundable or delisted agents cannot be filled and are blocked from protocol export. Keep 503A status current.