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AICAR Dosage Guide
Complete dosing protocol, reconstitution steps, and interactive calculator for AICAR.
Dosing & Reconstitution Guide
In rodent studies, AICAR is typically dosed at 0.5–1.5 mg/g (500–1500 mg/kg) via injection. These studies do not translate to human use or safety.
Standard / Gradual Approach
50mg VialstandardPhaseDoseVolume
Weeks 1–21,000 mcg (1 mg)6 units (0.06 mL)
Weeks 3–42,000 mcg (2 mg)12 units (0.12 mL)
Weeks 5–83,000 mcg (3 mg)18 units (0.18 mL)
Standard / Gradual Approach
50mg VialadvancedPhaseDoseVolume
Weeks 1–22,000 mcg (2 mg)12 units (0.12 mL)
Weeks 3–63,000 mcg (3 mg)18 units (0.18 mL)
Weeks 7–125,000 mcg (5 mg)30 units (0.30 mL)
Protocol Summary
Intravenous (IV): Once · Dose range 30–100 mg with gradual titration
Cycle Length: 4–8 weeks typical; reassess before extending
Frequency & Cycling
IV
Administer 50 mg/kg IV once daily, commonly in the morning or before exercise. Cycle for 4–8 weeks, followed by an equal or longer off period. Do not exceed 8-week continuous cycles due to potential AMPK desensitization. Often used in metabolic or endurance performance protocols.
🧪 Quick Start
Vial Size
50 mg
BAC Water
3 mL
Concentration
16700 mcg/unit
Starting Dose
1,000 mcg (1 mg) (6 units (0.06 mL))
Maintenance Dose
3,000 mcg (3 mg) (18 units (0.18 mL))
🧮 Dose Calculator
Concentration
166.7
mcg/unit
Draw Volume
3
units (0.030 mL)
For a 500 mcg dose, draw 3 units on a U-100 insulin syringe