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LL-37 Dosage Guide

Complete dosing protocol, reconstitution steps, and interactive calculator for LL-37.

Dosing & Reconstitution Guide

Research doses range from 1–5 μg/mL in vitro, or 1–10 mg/kg in animal models. LL-37 is not approved for use outside of the laboratory.

Standard / Gradual Approach

5mg Vialstandard
PhaseDoseVolume
Week 150 µg3 units (0.03 mL)
Week 2100 µg6 units (0.06 mL)
Week 3150 µg9 units (0.09 mL)
Week 4200 µg12 units (0.12 mL)
Week 5250 µg15 units (0.15 mL)
Week 6300 µg18 units (0.18 mL)
Week 7350 µg21 units (0.21 mL)
Week 8400 µg24 units (0.24 mL)

Protocol Summary

Topical: Applied once or twice daily depending on site and indication · Dose range 0.52 mg with gradual titration
Subcutaneous (SQ): Daily or every other day depending on inflammatory severity · Dose range 100400 mcg with gradual titration
Cycle Length: 4–8 weeks typical; reassess before extending

Frequency & Cycling

SubQ Injection

200–400 mcg daily or every other day for 4–6 weeks. Repeat cycles as needed with immune monitoring.

Topical

Apply to affected area once or twice daily. Safe for use in infected wounds, burns, or epithelial inflammation.

🧪 Quick Start

Vial Size
5 mg
BAC Water
3 mL
Concentration
1700 mcg/unit
Starting Dose
50 µg (3 units (0.03 mL))
Maintenance Dose
400 µg (24 units (0.24 mL))

🧮 Dose Calculator

Concentration
16.7
mcg/unit
Draw Volume
30
units (0.300 mL)
For a 500 mcg dose, draw 30 units on a U-100 insulin syringe