Back to MK-677 (Ibutamoren)
MK-677 (Ibutamoren) Dosage Guide
Complete dosing protocol, reconstitution steps, and interactive calculator for MK-677 (Ibutamoren).
Dosing Guide
In research studies, MK-677 has been administered orally at 10–25 mg per day over periods ranging from 2 to 12 weeks. These dosing protocols are used in tightly controlled clinical trials and are not approved for general use..
Standard / Gradual Approach
standardPhaseDose
Week 1-210 mg daily at bedtime
Week 3-415-20 mg daily at bedtime
Week 5+25 mg daily at bedtime
Protocol Summary
Oral: Once daily, typically in the evening · Dose range 10–30 mg with gradual titration
Cycle Length: 4–8 weeks typical; reassess before extending
Frequency & Cycling
Oral
Take once daily for 8–12 weeks. Breaks of 2–4 weeks recommended to monitor insulin sensitivity. Best taken pre-sleep or fasted in AM.
💊 Quick Start
Starting Dose
10 mg daily (oral)
Maintenance Dose
25 mg daily (oral)
🧮 Dose Calculator
Concentration
25.0
mcg/unit
Draw Volume
20
units (0.200 mL)
For a 500 mcg dose, draw 20 units on a U-100 insulin syringe