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MOTS-c Dosage Guide
Complete dosing protocol, reconstitution steps, and interactive calculator for MOTS-c.
Dosing & Reconstitution Guide
Rodent studies typically administer MOTS-c at 5–15 mg/kg intraperitoneally. No clinical or approved dosing exists for human use.
Standard / Gradual Approach
60mg VialstandardPhaseDoseVolume
Weeks 1–25 mg (5000 mcg)25 units (0.25 mL)
Weeks 3–47.5 mg (7500 mcg)37.5 units (0.375 mL)
Weeks 5–810 mg (10,000 mcg)50 units (0.50 mL)
Standard / Gradual Approach
60mg VialadvancedPhaseDoseVolume
Weeks 1–25 mg (5000 mcg)25 units (0.25 mL)
Weeks 3–410 mg (10,000 mcg)50 units (0.50 mL)
Weeks 5–815 mg (15,000 mcg)75 units (0.75 mL)
Standard / Gradual Approach
15mg VialstandardPhaseDoseVolume
Weeks 1–25 mg (5000 mcg)100 units (1.0 mL)
Protocol Summary
Subcutaneous (SQ): 3 times per week · Dose range 5–15 mg with gradual titration
Cycle Length: 4–8 weeks typical; reassess before extending
Frequency & Cycling
SubQ Injection
Standard Protocol: 10 mg subQ injection, 3 times per week. Alternative Protocol: 5 mg daily subQ injections for 4 weeks, then reassess.
🧪 Quick Start
Vial Size
10 mg
BAC Water
3 mL
Concentration
3300 mcg/unit
Starting Dose
200 mcg (0.2 mg) (3 units (0.03 mL))
Maintenance Dose
1,000 mcg (1.0 mg) (15 units (0.15 mL))
🧮 Dose Calculator
Concentration
33.3
mcg/unit
Draw Volume
15
units (0.150 mL)
For a 500 mcg dose, draw 15 units on a U-100 insulin syringe