Back to Semaglutide
Semaglutide Dosage Guide
Complete dosing protocol, reconstitution steps, and interactive calculator for Semaglutide.
Dosing & Reconstitution Guide
Start at low dose to minimize GI side effects. Do not combine with other incretin-based therapies unless supervised.
Standard / Gradual Approach
0.25mg VialstandardPhaseDoseVolume
Week 10.25mg200 units
Week 50.5mg400 units
Week 91mg800 units
Week 131.5-2.4mg1 units
Protocol Summary
Subcutaneous (SQ): Once weekly · Dose range 0.25–2.4 mg with gradual titration
Cycle Length: 4–8 weeks typical; reassess before extending
Frequency & Cycling
SubQ Injection
Typical protocol: 0.25 mg/week for 4 weeks → 0.5 mg → 1 mg → 1.7 mg → 2.4 mg. Duration 12–24 weeks. Break for 4–6 weeks between cycles.
🧪 Quick Start
Vial Size
0.25 mg
BAC Water
2 mL
Concentration
100 mcg/unit
🧮 Dose Calculator
Concentration
1.3
mcg/unit
Draw Volume
400
units (4.000 mL)
For a 500 mcg dose, draw 400 units on a U-100 insulin syringe