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Thymogen
Immune ModulationThymogen is a thymic-derived short peptide immunomodulator that promotes T-cell activity, immune rebalancing, and resistance to infection. It is widely used in Eastern European protocols to support immune function, particularly in cases of immunodeficiency, chronic infection, or age-related immune decline.
Reconstitute
10 mL BAC + 20mg vial
20 mcg/unit
Daily Range
50–150 mcg Subcutaneous (SQ)
Once daily
Standard Dose
100 mcg
Cycle
4–8 weeks
then reassess
Thymogenimmune modulatorT-cell peptideinfection defensethymic peptide
Dosing & Reconstitution Guide
Doses of 100–200 μg daily have been reported in regional medical trials. Thymogen is not approved in the U.S. and should only be used in research contexts.
Standard / Gradual Approach
standardPhaseDoseVolume
Days 1-54mg
Days 6-108mg
Days 11-1512mg
Days 16-2020mg
Protocol Summary
Subcutaneous (SQ): Once daily · Dose range 50–150 mcg with gradual titration
Cycle Length: 4–8 weeks typical; reassess before extending
Frequency & Cycling
SubQ Injection
Administer daily for 10–14 days. Repeat cycle every 3–6 months or as needed based on immune status.
🧪 Quick Start
BAC Water
10 mL
Potential Benefits & Use Cases
Thymogen is not authorized for human use in the U.S. All data presented reflect experimental or region-specific medical research.
Shown to support T-cell function and immune normalization
Studied for prevention of immune dysfunction under physical stress
Explored for reduction of inflammatory cytokines in vitro
Used in Russian trials for respiratory and chronic infections
May modulate oxidative stress and immune senescence in aging models
Clinical data Strong preclinical Limited data
Mechanism of Action
→Stimulates thymus-derived lymphocyte differentiation
→Enhances T-cell receptor expression and immunologic memory
→Regulates cytokine production and immune signaling cascades
Lifestyle & Optimization
timing
Consistent daily dosing.
diet
Vitamin-rich diet (especially vitamin C and D). Avoid smoking.
exercise
Exercise moderately 3–4 times weekly.
sleep
Sleep 8+ hours nightly for immune function. Manage stress.
Peptide Research & Preclinical Studies
Evidence-Based Research Findings
Side Effects & Safety
Common Side Effects
• Redness or soreness at injection site
• Mild fatigue
Contraindications & Warnings
• Not recommended for use in autoimmune disorders due to potential for immune overstimulation
Long-Term Safety Data
• May lead to immune exhaustion or imbalance with extended use; monitor in chronic administration
🧮 Dose Calculator
Concentration
20.0
mcg/unit
Draw Volume
25
units (0.250 mL)
For a 500 mcg dose, draw 25 units on a U-100 insulin syringe
🧬
Bioavailability & Absorption
SubQ Injection
High systemic absorption and lymphatic distribution when administered subcutaneously
Oral Administration
Poor oral bioavailability due to enzymatic degradation in the stomach
Half-Life
Approximately 60 minutes
Degradation
Broken down by proteases in plasma and liver
Tissue Specificity
Preferentially targets thymus, spleen, and peripheral immune cells
⚗️
Peptide Details
Molecular Weight
453.53
Formula
C22H33N6O5
Sequence
H-Ala-Lys-Glu-Asp-OH
⚖️
Legal Status & Regulatory
RegionStatus
FDANot Approved
EUNot Approved
AustraliaNot Approved
CanadaNot Approved
Storage Instructions
Lyophilized (Powder)
Store lyophilized powder at 2-8°C
Reconstituted (Mixed)
After reconstitution, maintain at 2-8°C and use within 24 hours. Thymogen should be used fresh.