Back to Tirzepatide

Tirzepatide Dosage Guide

Complete dosing protocol, reconstitution steps, and interactive calculator for Tirzepatide.

Dosing & Reconstitution Guide

GI effects dose-dependent. Avoid combining with GLP-1 agonists unless supervised.

Standard / Gradual Approach

2.5mg Vialstandard
PhaseDoseVolume
Week 12.5mg200 units
Week 55mg400 units
Week 910mg800 units
Week 1315mg1200 units

Protocol Summary

Subcutaneous (SQ): Once weekly · Dose range 2.515 mg with gradual titration
Cycle Length: 4–8 weeks typical; reassess before extending

Frequency & Cycling

Subcutaneous

Start with 2.5mg once weekly for 4 weeks, then increase to 5mg once weekly for 4 weeks. Continue increasing by 2.5mg every 4 weeks until reaching the maximum dose of 15mg once weekly or the maximum tolerated dose.

🧪 Quick Start

Vial Size
2.5 mg
BAC Water
2 mL
Concentration
1300 mcg/unit

🧮 Dose Calculator

Concentration
12.5
mcg/unit
Draw Volume
40
units (0.400 mL)
For a 500 mcg dose, draw 40 units on a U-100 insulin syringe